sodium polystyrene sulfonate contraindications

Patients with hypokalemia; hypersensitivity to Kayexalate. Sodium polystyrene sulfonate can bind to calcium, iron, magnesium, and other minerals in the gastrointestinal tract. Polystyrene sulfonate is usually supplied in the sodium and calcium form. Manufacturers advise take other drugs at least 3 hours before or after calcium- or sodium-polystyrene sulfonate; a 6-hour separation should be considered in gastroparesis. : combo may decr. Hypokalemia. in vitro . Brand names for sodium polystyrene sulfonate-powder are Kalexate, Kayexalate, Kionex, and SP. sodium polystyrene sulfonate + aluminum hydroxide avoid combo w/ oral sodium polystyrene sulfonate or use alternative; interaction less likely w/ rectal admin. Haupt HM and Hutchins GM, "Sodium Polystyrene Sulfonate Pneumonitis," Arch Intern Med, 1982, 142(2):379-81. Pharmacokinetics: Excretion: Exchanged resin eliminated in the faeces. Pms-Sodium Polystyrene Sulfonate; Descriptions. It is a potassium-binding ion-exchange resin that can be administered orally (25 grams in … Potassium-removing action: Sodium polystyrene sulfonate is a cation-exchange resin that releases sodium in exchange for other cations in the GI tract. Polystyrene sulfonate affects the exchange of sodium and potassium in the body. Rectal administration of suspension with sorbitol in neonates, particularly in premature infants. sodium polystyrene sulfonate/slt cation-donating antacids Full Drug Information Selected from data included with permission and copyrighted by First Databank, Inc. Consult physician about restricting sodium content from dietary and other sources since drug contains approximately 100 mg (4.1 mEq) of sodium per gram (1 tsp, 15 mEq sodium). Description: Sodium polysytrene sulfonate exchanges sodium ions for potassium ions and other cations in the GI tract before the resin is excreted in the faeces. Polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. SDS; Poly(4-styrenesulfonic acid) solution. Cautions Find out what health conditions may be a health risk when taken with Sodium Polystyrene Sulfonate Oral 36 The resin causes constipation and hence is almost always given with a cathartic. risk of metabolic alkalosis; may incr. Sodium polystyrene sulfonate - reference spectrum. Obstructive bowel disease. Sodium polystyrene sulfonate is usually taken or used one to four times a day. KAYEXALATE, brand of sodium polystyrene sulfonate is a benzene, diethenyl-polymer, with ethenylbenzene, sulfonated, sodium salt and has the following structural formula: The drug is a cream to light brown finely ground, powdered form of sodium polystyrene sulfonate, a cation-exchange resin prepared in the sodium phase with an in vitro exchange OBJECTIVE: The objective of this study was to determine whether use of a hyperkalemia order set is associated with appropriate use of SPS. Assess abdomen and note character and frequency of stools. If necessary, sodium polystyrene sulfonate may be administered into the stomach through a plastic tube. The suspension may also be given rectally as an enema. sodium polystyrene sulfonate potassium-binding efficacy; may incr. It however is unclear if it works and there is concern about possible side effects when it is mixed with sorbitol. WebMD provides common contraindications for Sodium Polystyrene Sulfonate Oral. RESONIUM CALCIUM (calcium polystyrene sulfonate) is a cation exchange resin prepared in the calcium phase. Discontinue sodium polystyrene sulfonate if patient becomes constipated. Sodium polystyrene sulfonate may decrease your absorption of other medications. Polystyrene sulfonate is usually supplied in either the sodium or calcium form. Neonates with reduced gut motility (postoperative or drug-induced), oral administration. Use a non-sodium-containing cleansing enema after each dose as directed. KAYEXALATE is a cation-exchange resin prepared in the sodium phase, with an in vivo exchange capacity of approximately 1 mmol (in vitro approximately 3.1 mmol) of potassium per gram. Commercially Available Suspension Shake the suspension well before administering. It is used as a potassium binder in acute and chronic kidney disease for people with hyperkalemia (abnormal high blood serum potassium levels). The dosage and length of treatment are based on your medical condition and response to treatment. This may inactivate both sodium polystyrene sulfonate and the mineral it binds to and reduce the effectiveness of both medications. Unformatted text preview: ACTIVE LEARNING TEMPLATE: Medication Jordan Williams STUDENT NAME_____ Sodium Polystyrene Sulfonate (Kayexalate) MEDICATION_____ REVIEW MODULE CHAPTER_____ exchange resins CATEGORY CLASS__cationic _____ PURPOSE OF MEDICATION Expected Pharmacological Action Binds potassium ions in the GI lumen, increasing fecal potassium excretion … Sodium polystyrene sulfonate (SPS) is a common treatment option for hyperkalemia. Onset: 2-24 hr. References: Belanger DR, Tierney MG, and Dickinson G, "Effect of Sodium Polystyrene Sulfonate on Lithium Bioavailability," Ann Emerg Med, 1992, 21(11):1312-5. Sodium polystyrene sulfonate (SPS, Kayexalate, Kionex) is a cation exchange resin that exchanges sodium for secreted K in the colon. Take or use sodium polystyrene sulfonate at around the same time(s) every day. Before Using; Portions of this document last updated: Feb. 01, 2021. Contraindications. Each gram of resin binds approximately 0.65 mmol of K in vivo, although the effect is highly variable and unpredictable. Malone TA, "Glucose and Insulin Versus Cation-Exchange Resin for the Treatment of Hyperkalemia in Very Low Birth Weight … However, it is unclear if it is beneficial and there is concern about possible side effects when it is combined with sorbitol. This medicine is available only with your doctor's prescription. You need a prescription to obtain this drug. Sodium polystyrene sulfonate comes as a suspension and as an oral powder for suspension to take by mouth. High levels of potassium ion are found in the large intestine and therefore are exchanged and eliminated. Sodium polystyrene sulfonate binds to many commonly prescribed oral medicines, decreasing the absorption and therefore the effectiveness of those oral medicines. 1 Product Result | Match Criteria: Product Name Y0000210 ; European Pharmacopoeia (EP) pricing. Use sodium polystyrene sulfonate rectally as an enema as directed by your doctor, usually every 6 hours as needed. Each gram of resin has a theoretical in vitro exchange capacity of about 1.3 to 2 millimoles (mmol) of potassium (K+). Individual interactants: Polystyrene sulfonate Sodium polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. The sodium content is approximately 100 mg (4.1 mEq) per gram of the drug. Hypersensitivity to polystyrene sulfonate resins. The drug is a cream to light brown finely ground, powdered form of sodium polystyrene sulfonate, a cation-exchange resin prepared in the sodium phase with an in vitro exchange capacity of approximately 3.1 mEq (in vivo approximately 1 mEq) of potassium per gram. KAYEXALATE is a benzene, diethenyl-polymer, with ethenylbenzene, sulfonated, sodium salt and has the following structural formula: The drug is a cream to light brown finely ground, powdered form of sodium polystyrene sulfonate, a cation-exchange resin prepared in the sodium phase with an . Sodium Polystyrene Sulfonate is contraindicated in the following conditions: patients with hypokalemia, patients with a history of hypersensitivity to polystyrene sulfonate resins, obstructive bowel disease, neonates with reduced gut motility (postoperatively or drug induced) and oral administration in neonates. 1 … Sodium polystyrene sulfonate was initially approved by the US FDA in 1958. In vivo, the actual amount of potassium bound will be less than this. KAYEXALATE (sodium polystyrene sulfonate) is a cream or light brown fine powder of sodium polystyrene sulfonate. The sodium content is approximately 4.1 mmol The drug is a cream to light brown finely ground, powdered form of sodium polystyrene sulfonate, a cation-exchange resin prepared in the sodium phase with an in vitro exchange capacity of approximately 3.1 mEq (in vivo approximately 1 mEq) of potassium per gram.The sodium content is approximately 100 mg (4.1 mEq) per gram of the drug. Sodium polystyrene sulfonate-powder is avaiabe in generic form. SODIUM POLYSTYRENE SULFONATE (pol-ee-stye'reen) Kayexalate, SPS Suspension ... Contraindications. To aid health-care professionals, a hyperkalemia order set was created at a 979-bed community teaching hospital. Contraindications. Keep the enema in the rectum for several hours, if possible. It is used as a potassium binder in acute and chronic kidney disease for people with hyperkalaemia (abnormal high blood serum potassium levels). Concurrent low-sodium diet may be ordered for patients with HF In patients receiving concurrent digoxin, assess for symptoms of digoxin toxicity (anorexia, nausea, vomiting, visual disturbances, arrhythmias).

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