ravindra gupta age

Ravindra Kumar (born 1959) is a Political Scientist, Peace Educator, an Indologist, a Humanist, Cultural Anthropologist, Gandhian Thinker, and a Former Vice-Chancellor of CCS University, Meerut (India). HIV Elite Controllers may reveal insights into virus persistence given they harbour small reservoir sizes, akin to HIV non-controllers treated early with combination antiretroviral therapy. See the complete profile on LinkedIn and discover Dr. Ravindra’s connections and jobs at Moreover, protease inhibitor resistance-associated mutations can arise in gag in the absence of protease mutations in vitro. The participant characteristics of those with and without an L74I mutation were similar, with an overall median age of 30 years, two-thirds were female and the median CD4 cell count at first-line VF was 142 cells/mm 3 (IQR = 641). Therapy failure may occur because of incomplete ART adherence and possibly viral replication at some reservoir sites. ,T�d=ɩ���$��I��P7환i��L�>)陉%+sڹ�4mW�}9M2�ͧ #x�8��n����Ã������ɭ�o�0��\�7R���0C٢����+�6�����Ou���.�E�a�f�X�A�11Χb(�����ގk㪚r9� ��J1��.��-�I�`�z�����>�_n�O��r���gt��q�%�%?x�Hl��_l�M���kh8�:� ��Ċb�!�I Inferred maximum likelihood phylogenetic tree of single genome derived HIV-1 env sequences. Due to our privacy policy, only current members can send messages to people on ResearchGate. We wished to assess the contribution of full-length Gag to protease inhibitor susceptibility in viruses unexposed... Join ResearchGate to find the people and research you need to help your work. Gupta, R. K. et al. (DOCX), Summary of Sequences from Individuals Receiving NRTI/NNRTI First-Line Regimens. (DOCX), Proportion of Different Codons at Position 103 in HIV-1 RT Sequences from 26,358 Individuals in the Stanford HIV Drug Resistance Database From Six Low- and Middle-Income Country Regions. Professor Ravindra "Ravi" Kumar Gupta is a professor of clinical microbiology at the Cambridge Institute of Therapeutic Immunology and Infectious Disease at the University of Cambridge. This review attempts to summarize the latest data on this subject. Cambridge physician and microbiologist Professor Ravindra Kumar Gupta is one of six persons of Indian-origin on the latest Time 100 Most Influential … Here we perform the first proof of concept viral GWAS... BACKGROUND: University students and faculty, institute members, and independent researchers, Technology or product developers, R&D specialists, and government or NGO employees in scientific roles, Health care professionals, including clinical researchers, Journalists, citizen scientists, or anyone interested in reading and discovering research. Join Facebook to connect with Ravindra Gupta and others you may know. Antibodies from SARS-CoV-2 infection neutralize the virus by focused targeting of Spike and there is limited serum cross-neutralization of the closely-related SARS-CoV. Join ResearchGate to contact this researcher and connect with your scientific community. Rapid COVID-19 diagnosis in hospital is essential for patient management and identification of infectious patients to limit the potential for nosocomial transmission. Ravindra R Gupta, age 50 Ravindra R Gupta is a fifty year old individual. Major protease mutations are rarely observed following failure with protease inhibitors (PI), and other viral determinants of failure to PI are poorly understood. Major protease mutations are rarely observed following first-line failure with PIs and interpretation of genotyping results in this context may be difficult. He is also a member of the faculty of the Africa Health Research Institute in Durban, South Africa. Th... Nucleic acid amplification for the detection of SARS-CoV-2 RNA in respiratory samples is the standard method for diagnosis. Dr. Gupta graduated from the Ohio State University College of Medicine in 2008. Sorry, you need to be a researcher to join ResearchGate. We're 100% free for everything! We can't detect anything," said Ravindra Gupta, a professor and HIV biologist who co-led a team of doctors treating the man. We report an evaluation of point of care (POC) nucleic acid amplification testing (NAAT) in 149 participants with parallel combined nasal/throat swabbing for POC versus standard lab RT-PCR testing. Independent replication of HIV in the central nervous system despite ART, so-called... Background: Whitepages people search is the most trusted directory. HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: A systematic review and meta-regression analysis, DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV‐1 infection of macrophages, Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation, Virological Outcomes of Second-line Protease Inhibitor-Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis, Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration, Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa, A G1‐like state allows HIV‐1 to bypass SAMHD1 restriction in macrophages, Occult HIV-1 drug resistance to thymidine analogues following failure of first-line tenofovir combined with a cytosine analogue and nevirapine or efavirenz in sub Saharan Africa: a retrospective multi-centre cohort study, Wide variation in susceptibility of transmitted/founder HIV-1 subtype C Isolates to protease inhibitors and association with in vitro replication efficiency, Genome-wide association study of HIV whole genome sequences validated using drug resistance, Sequential CCR5-Tropic HIV-1 Reactivation from Distinct Cellular Reservoirs following Perturbation of Elite Control, Correction: Evidence for Reduced Drug Susceptibility without Emergence of Major Protease Mutations following Protease Inhibitor Monotherapy Failure in the SARA Trial, HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing, Evidence for Reduced Drug Susceptibility without Emergence of Major Protease Mutations following Protease Inhibitor Monotherapy Failure in the SARA Trial, Gag-Protease Sequence Evolution Following Protease Inhibitor Monotherapy Treatment Failure in HIV-1 Viruses Circulating in East Africa on behalf of the DART Virology Group and DART Trial Team, Immune evasion activities of accessory proteins Vpu, Nef and Vif are conserved in acute and chronic HIV-1 infection, Phenotypic characterization of virological failure following lopinavir/ritonavir monotherapy using full-length Gag-protease genes, The arrival of untreatable multidrug-resistant HIV-1 in sub-Saharan Africa, Vpx complementation of ‘non-macrophage tropic’ R5 viruses reveals robust entry of infectious HIV-1 cores into macrophages, High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy, Macrophages: The neglected barrier to eradication, Evolving uses of oral reverse transcriptase inhibitors in the HIV-1 epidemic: From treatment to prevention, Resistance at Virological Failure Using Boosted Protease Inhibitors Versus Nonnucleoside Reverse Transcriptase Inhibitors As First-Line Antiretroviral Therapy--Implications for Sustained Efficacy of ART in Resource-Limited Settings, Oral Antiretroviral Drugs as Public Health Tools for HIV Prevention: Global Implications for Adherence, Drug Resistance, and the Success of HIV Treatment Programs, Emergence of HIV Drug Resistance During First- and Second-Line Antiretroviral Therapy in Resource-Limited Settings, The "Silent" Global Burden of Congenital Cytomegalovirus, Interpretation of Resistance Data from Randomized Trials of First-Line Antiretroviral Treatment, Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: A global collaborative study and meta-regression analysis, HIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef, Impact of the N348I Mutation in HIV-1 Reverse Transcriptase on Nonnucleoside Reverse Transcriptase Inhibitor Resistance in Non-Subtype B HIV-1, Drug Resistance in Human Immunodeficiency Virus Type-1 Infected Zambian Children Using Adult Fixed Dose Combination Stavudine, Lamivudine, and Nevirapine, Full-length HIV-1 Gag determines protease inhibitor susceptibility within in-vitro assays. In the developed world, following the virtual elimination of circulating rubella, it is the commonest nongenetic cause of childhood hearing loss and an important cause of neurodevelopmental delay. In... A new subgroup of HIV-1, designated Group P, was recently detected in two unrelated patients of Cameroonian origin. Dynamic changes in HIV nucleic acids and total lymphocytes following ASCT. Termed the ‘Berlin patient’, the individual underwent two allogeneic haematopoietic stem-cell transplantation (allo-HSCT) procedures using a donor with a homozygous mutation in the HIV coreceptor CCR5 (CCR5Δ32/Δ32) to treat his acute myeloid leukaemia. We know 1 person related to this person. These changes are induced... Background: This pathway requires TLR4 engagement w... Background: Dr. Ravindra Gupta, MD is a internal medicine specialist in Falls Church, VA. Dr. Gupta completed a residency at University of North Carolina Hospitals. Multiple SARS-CoV-2 vaccines have shown protective efficacy, which is most likely mediated by neutralizing antibodies recognizing the viral entry protein, Spike. We show that HUSH-depletion in human cell lines and primary fibroblasts leads to induction of interferon-stimulated genes (ISGs) through JAK/STAT signaling. In a recent medRxiv preprint publication, the team led by Professor Ravindra K. Gupta has assessed the real-world immune responses following the vaccination against the SARS-CoV-2. �q�҉���+/p}({-�s�����L���]�c�i�ڎ �!vߴॊ�q�F�@;�Јj��w��X�t�YvȞ@���{�:hOmXp��3�)��lj��f�#:�c>��hL��P�{@&����i���V&֔�[)T?�Kk�d?�y�rZl䘦����$WcU�-:Xd���Ziそxs�a6u. Lookup the home address and phone 5162484469 and other contact details for this person Quick Facts Ravindra has an associate degree. : << /Length 5 0 R /Filter /FlateDecode >> Participants: patients presenting to hospital... Macrophages exist predominantly in two distinct states, G0 and a G1-like state that is accompanied by phosphorylation of SAMHD1 at T592. Strategies to curb the rise in PDR include using antiretrovirals (ARVs) with hig... HIV-1 cure remains elusive with only one reported case a decade ago1,2. delayed adaptive responses and systemic inflammation already ev... Little is known about the impact of pretreatment drug resistance (PDR) on the efficacy of second generation integrase inhibitors. Delay in responding to rising levels of PDR is projected to fuel a worldwide increase in mortality, HIV incidence and ART costs. The top state of residence is New Jersey, followed by California. Furthermore, the D614G spike mutant now dominates the pandemic and it is unclear how serological tests designed to detect anti-Spike antibodies perform against this variant. Additional figures and tables for secondary analyses of the data. Objectives (A) Infectious virus and (B) p24 release from 293T cells following cotransfection with a vpu- and nef-defective proviral HIV-1 NL4-3 construct, pCGCG plasmids expressing eGFP alone (eGFP only) or together with the indicated vpu or nef alleles and a human or gorilla tetherin expression plasmid. SAMHD1 suppresses viral reverse transcription (RT) through depletion of cellular dNTPs but is naturally switched off by phosphorylation in a subpopulation of MDM found in... Introduction: Methods: (photo taken from African Health Research Institute website) (photo taken from African Health Research Institute website) Among other Indians on Times 100 influential people for year 2020 include Prime Minister Narendra Modi, actor Ayushman Khurrana, the 'dadi from Shaheen Bhagh protest Bilkis, Alphabet and Google CEO Sunder Pichai. This observational cohort study was nested within t... Macrophages are the first line of defence against invading pathogens. Second-line antiretroviral therapy (ART) based on ritonavir-boosted protease inhibitors (bPIs) represents the only available option after first-line failure for the majority of individuals living with human immunodeficiency virus (HIV) worldwide. Dr. Gupta is board certified in Internal Medicine. Reema Gupta We found 15 records for Reema Gupta in Michigan, South Carolina and 8 other states.Select the best result to find their address, phone number, relatives, and public records. The replication capacity of all viruses in a variety of cell lines was impaired by N348I. With the increasing availability of whole genome sequences (WGS) for pathogens, it is important to establish whether GWAS of viral genomes could reveal important biological insights. See the complete profile on LinkedIn and discover Ravindra’s connections and jobs at similar companies. Objective To compare a point of care (POC) nucleic acid amplification based platform for rapid diagnosis of COVID-19 against the standard laboratory RT-PCR test and perform an implementation study. Ravindra K Goyal is a resident of NY. The CNS may serve as a reservoir site due to lowered ART penetration and virus production from long-lived... Background: "There is no virus there that we can measure. Reverse transcriptase inhibitors, the first licensed class of ART, have been at the forefront of tr... Background Increases in the prevalence of resistance to nonnucleoside reverse transcriptase inhibitors (NNRTIs) have been observed among previously untreated individuals in all areas of sub-Saharan Africa. CHAP2 (Children with HIV Antibiotic Prophylaxis 2) is a prospective cohort of Zambian children using d4T/3TC/NVP adult Triomune30 dosed according to WHO guidelines. They play a crucial role in immunity but also in regeneration and homeostasis. Dr. Gupta is affiliated with Northwestern Memorial Hospital. (DOCX), Absolute and Cumulative Percent of Each Major Nucleoside (NRTI) Drug-Resistance Mutation (DRM) in 467 Individuals with Virological Failure and Intermediate or High-Level Acquired NRTI Drug Resistance while Receiving a First-Line TDF Containing Regimen. Many countries have continued to use thymidine analogue drugs despite recommendations to use tenofovir in combination with a cytosine analogue and NNRTI as first-line ART. Methods: HIV-1 genotypic resistance test (GRT) interpretation systems (IS) require updates as new studies on HIV-1 drug resistance are published and as treatment guidelines evolve. Get current address, cell phone number, email address, relatives, friends and a lot more. Madhu V Gupta, Ravindra K Gupta, and two other persons are connected to this place. Both groups of patients represent the most promising candidates for interventions aimed at sustained remission or 'cure'. Find out why Ravindra Gupta is one of the 100 most influential people of 2020. (DOCX), Proportion of Different 24 Nucleotide Sequences Flanking Position 103 in HIV-1 RT Sequences from 26,358 Individuals in the Stanford HIV Drug Resistance Database From Six Low- and Middle-Income Country Regions. Supplementary Figures and Tables. The best result we found for your search is Ram B Gupta age 70s in Sterling Heights, MI. x�]ے�Ƒ}�W�ǖ����p��"��X�F��ʻ�_��ؠ����dP5C����ô�謬̓׺������W������b��_���z��a�۪�Ӷl�k���_�/ߧ��>���ɇahҦ)������ߗ�I��#�kz:ܦw ��n~w��-}�}���q؏���ƨ�&����c��1N��M���*�ɒ��r�]H�vk吞�������G���r��e�'�nߚ~HBg+��ww�S��3~��� ���wC��m�"�* Major resistance mutations are rarely present at treatment failure in patients receiving bPI and the determinants of failure in these patients remain unknown. Ravindra Gupta profile - I am a successful and trained choreographer in pune. AMFI Registered mutual fund distributor valid from 19-Sep-2016 valid upto 31-Aug-2019 located in Nagpur Buy/Sell Mutual funds sitting @ Home offering Cash Management, SIP Total body irradiation wa... HIV persists despite antiretroviral therapy (ART) in cellular reservoirs thought to occur in distinct anatomical compartments. Dr. Ravindra has 25 jobs listed on their profile. An AxxxAxxxW transmembrane motif that has been shown to be crucial for tetherin antagonism by HIV-1 Group M Vpus is highlighted in yellow. BACKGROUND: Narendra Modi, Ayushmann Khurrana, Sundar Pichai, Bilkis,and Ravindra Gupta are the Indians on the TIME’s 100 most influential people of 2020 … We investigated the efficacy of NRTI backbones (tenofovir or abacavir with a cytosine analogue) in low- and middle-income countries where there is significant prior exposure to antiretrovirals and drug resistance to NRTIs. Rapid COVID-19 diagnosis in hospital is essential, though complicated by 30-50% of nose/throat swabs being negative by SARS-CoV-2 nucleic acid amplification testing (NAAT). … We aimed to estimate changes in the prevalence of HIV-1 drug resistance in treatment-naive individuals with HIV since ini... Alignment of SIVgor, HIV-1 M and P Vpus. Gattamraju Ravindra Kumar (born 15 June 1961) is an Indian laser physicist and a senior professor of Nuclear and Atomic Physics at Tata Institute of Fundamental Research.Known for his research on Ultrashort pulse and Warm dense matter, Kumar is an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy. The majority of this testing is centralised and therefore turnaround times of several days. Identical sequences have been collapsed and a single representative sequence left in the alignment to build the tree. © 2008-2021 ResearchGate GmbH. Setting: a large UK teaching hospital Age-related heterogeneity in immune responses to SARS-CoV-2 following BNT162b2 vaccination Dami A. Collier1,2,3*, Isabella A.T.M. We therefore characterized Gag-Protease phenotypic susceptibility in subtype A and D viruses circulating in East Africa following viral rebound on PIs. AIDS 24 , 1651–1655 (2010). UK policy in 2021 is to extend the dosing interval from three to twelve weeks. The movement from first-generation antiretroviral therapy (ART) coformulations based on thymidine analogues to second-generation ART coformulations based on tenofovir may co... Introduction: The gag gene is highly polymorphic across HIV-1 subtypes and contributes to susceptibility to protease inhibitors (PI), a critical class of antiretrovirals that will be used in up to 2 million individuals as second-line therapy in sub Saharan Africa by 2020. Each new infection has significant economic, social and human costs and prevention efforts are now as great a priority as global antiretroviral therapy (ART) scale up. Voting in Matia Mahal Assembly was held on 8 February in which 70.33% voters exercised their vote. inflammation, is characteristic of asymptomatic or mild disease. The Human Silencing Hub (HUSH) complex is necessary for epigenetic repression of LINE-1 elements. Since the advent of ART, the spectrum of HIV-associated neurocognitive disorder (HAND) has shifted from the most severe form to milder forms. (DOCX), Prevalence of Protease Inhibitor (PI) Drug-Resistance Mutations (DRMs) in PI-Naïve and -Treated Individuals and Their Estimated Contributions to Reduced PI Susceptibility. This effect is mainly attributed to MDA5 and RIG-I sensing of double-stranded RNAs (dsRNAs). Here we report chronic SARS-CoV-2 with reduced sensitivity to neutralising antibodies in an immune suppressed individual treated with convalescent plasma, generating whole genome ultradeep sequences over 23 time points spanning 101 days... Background

Tesla Model Y Australia Delivery, Cho Oyu Expedition, Vern Yip Chinoiserie, Fc Dallas Vs Colorado Prediction, Ardun Flathead Horsepower, Polly Guitar Chords, Old Carriage Trail Map, Don Oliver Weights Canada, Words Associated With Snakes,